Abstract
Since 1980 when deep-brain stimulation (DBS) was first described for movement disorders, 1 Brice J McLellan L Suppression of intention tremor by contingent deep-brain stimulation. Lancet. 1980; 315: 1221-1222 Summary Scopus (123) Google Scholar there have been substantial technical advances in DBS hardware and brain imaging. Thalamic DBS is an established treatment for Parkinson's disease 2 Benabid AL Pollack P Gao D et al. Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorder. J Neurosurg. 1996; 84: 203-214 Crossref PubMed Scopus (961) Google Scholar but its value in movement disorders due to multiple sclerosis (MS) is uncertain, although one study suggested good results in 69% of patients. 3 Geny C Nguyen J-P Pollin B et al. Improvement of severe postural cerebellar tremor in multiple sclerosis by chronic thalamic stimulation. Mov Disord. 1996; 11: 489-494 Crossref PubMed Scopus (127) Google Scholar We are prospectively evaluating thalamic DBS in MS patients and report our preliminary results.
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