Abstract
The present study was conducted to evaluate the histopathological effects of diluted cotton textile dyeing and printing effluent on the testes of mice. To evaluate the effects of dose and duration dependent in vivo exposure of textile dyeing and printing effluent, the toxic stress was imposed by a daily oral administration of 5, 10, 15 and 20 % /kgbody weight (bw)/day doses of diluted effluent for 2, 4 and 6 days exposure durations.Results revealed marked histopathological damages in the mice testes. The testes of the experimental groups showed distinct histological lesions. Few of the observed lesions include severe damages within the seminiferous tubules, changes in spermatocytes, scattered spermatids, degeneration and severe necrosis in the sertoli cells.Results of thepresent study suggested that the dose and duration dependent exposure oftextile dyeing and printing industry effluentsinducedseveral significant histopathological lesions in the testes of mice. It was also observed that the toxic effects in terms of the histopathological lesions were more of exposure duration dependent.
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