Abstract
The title compound, C 7 H 11 NOS, an analogue of biotin, was prepared in order to further investigate the binding characteristics of biotin. The bicyclic ring system has pseudo-mirror symmetry with the tetrahydrothieno ring in an S5β-envelope form with the methyl substituent in an equatorial position. The cis-fused pyrrolidone system is planar [non-H atoms coplanar within 0.03 (1) A] and the dihedral angle between it and the four coplanar C atoms of the tetrahydrothieno ring is 119.0(2)°. The C-S bond lengths are 1.808 (4) and 1.803(4)A, and the C-S-C angle is 88.8 (2)°.
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More From: Acta Crystallographica Section C Crystal Structure Communications
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