Abstract
Total solar radiation contains approximately 10% ultraviolet light. Ultraviolet rays have benefits such as providing warmth, light, and helping to synthesise vitamin D3. However, ultraviolet rays can also have negative impacts on the skin such as browning, hyperpigmentation, erythema, and premature ageing. Natural sunscreens with high SPF are useful in reducing the negative effects of ultraviolet rays. This study aims to determine anti-UV activity, SPF value, and assessment of human skin irritation or allergy to sunscreen cream from Ipomoea pes-caprae leaves. Anti-UV activity test and SPF value determination were carried out in vitro using UV-Vis Spectrophotometry. Irritation testing was conducted using the patch test method for 6 hours. The results showed that Ipomoea pes-caprae has anti-UV-A and anti-UV-B activities. Ipomoea pes-caprae leaf extract provides extra protection at a concentration of 2000 ppm. The irritation test of the cream on human skin found no skin abnormalities such as edema, urticaria, irritation and edema.
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