Testing of inactivated vaccine against IB, ND and EDS-76 of domestic and imported production

Abstract

Currently, the Russian poultry industry uses a wide arsenal of various associated inactivated vaccines that allow for effective prevention of infectious diseases. However, a significant share of vaccines used in Russia is represented by imported drugs. Such a situation in connection with the current geopolitical events indicates the need to focus on the production and use of high-quality domestic analogues of foreign drugs.Therefore, the purpose of this work was to conduct a comparative analysis of the use of inactivated associated vaccine against avian infectious bronchitis (IB), Newcastle disease (ND) and egg drop syndrome-76 (EDS-76) of domestic and imported production.To achieve this goal, two commercial samples of the associated inactivated emulsion vaccine against IB, ND and EDS76 were tested. The first sample of domestic production, the second foreign (Israel).The determination of the harmlessness and antigenic activity of both vaccine samples was carried out on 90-day-old egg chickens simultaneously.The results obtained allowed us to conclude that the samples of inactivated emulsion vaccine against IB, ND and EDS76 of domestic and imported production are harmless, have high antigenic activity, they are at the same level of indicators for the antigenic components included in their composition and for effectiveness.