Abstract

SummaryScreening of pooled urine samples was suggested during the Second World War as a method of detecting syphilis in US soldiers. Recently, pooling has been used in screening blood for Human Immunodeficiency Virus (HIV) antibody to help curb the further spread of the deadly virus. Pooling reduces the cost and also reduces the rates of false‐negative results in samples that are not disease‐free, a factor that has led to pooling not being adopted as an efficient procedure for screening HIV. This paper generalizes a common pooling strategy with retesting, and discusses its characteristics. Furthermore, it suggests a new testing strategy with retesting.

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