Abstract
The term microalbuminuria is used to describe albumin concentrations in the urine that are greater than normal but not detectable with common urine dipstick assays. Microalbuminuria has been found to predict the occurrence of clinical nephropathy in type I diabetes, and to a lesser extent, in type II diabetes. Recent studies have shown that the normalization of blood glucose and blood pressure can delay the progression from microalbuminuria to clinical nephropathy. While recommendations have been made for yearly urine albumin testing for diabetic patients, there is great divergence in urine collection techniques and measurement systems. I recommend collection of a timed overnight specimen, quantitative measurement of albumin and creatinine, and the reporting of the albumin excretion rate and the ratio of albumin/creatinine.
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