Abstract
Testicular plasmacytomas are rare tumors presenting in most cases with painless testicular swelling. Testicular involvement may occur as a first manifestation of plasma cell disorder or following diagnosis of systemic plasma cell myeloma. We report a case of a 49-year-old man who was found to have IgG-λ type multiple myeloma and spinal cord compression at Th 7-9 level. After spinal radiotherapy, he was treated with VAD chemotherapy. Just before the second cycle of VAD he admitted with left testicular swelling. Surgical orchiectomy of his left testis was performed. Histological and immunohistochemical studies of surgical material established massive interstitial plasma cell infiltration with strong anti-IgG and anti-λ antisera staining. Soon after the surgery he died of worsening renal failure and progressive myeloma. We present here a fatal case with an aggressive form of plasma cell myeloma with widespread bone disease along with extramedullary involvement of testis.
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