Testicular tumors: A histopathological study of 50 cases

Abstract

Background: Pattern of a disease is studied with the idea of getting information about the clinical presentation, the morphology and the causative factors. The testicular tumors constitute 4th most common cause of death from neoplasia in younger males. Though the etiology of testicular cancers is not well understood, various factors like cryptorchidism, trauma infections and genetics play role in the disease. The testicular tumors are histologically diverse. Aim: Our study was undertaken to study the clinical presentation and morphological patterns of the testicular tumors. A total number of 50 cases of testicular tumors were studied. The majority of the cases i.e. 48 (96%) were of germ cell origin. Only 2 cases (4%) of testicular lymphoma were reported. Materials and Methods: The study was carried out in two parts – retrospective (2005-2007) and prospective (2008-2010). During this period a total number of 50 cases of testicular tumors were diagnosed on small biopsies and orchidectomy specimens. Results: The study work comprised of 50 cases of testicular tumors among which 44 (88%) cases were malignant and 6 (12%) were benign (Table 1). The majority of the testicular tumors i.e. 48 cases (96%) were of germ cell origin. Only 2 cases (4%) of testicular lymphoma were reported (Table 2). No case of sex cord stromal tumor, mixed germ cell sex cord tumor and metastatic tumor was reported. Conclusion: Tumors of the testes present a great variety of histological types with many structural variations. The present study fairly provides an insight into the clinical presentations, prevalence and patterns of testicular tumors. Keywords: Testicular tumors, Lymphoma, Seminomas, Germ cell tumor