Abstract

By cutting the distal part of gubernaculum testis in newborn rats cryptorchism was produced. This new method to obtain cryptorchid animals has the advange of preventing testicular descent before it normally takes place, thus mimicking congenital cryptorchism. Unilaterally cryptorchid rats were examined at 20, 30 and 100 days of age. Morphometric methods were used to compare the structure of the abdominal and the scrotal testicles during development. In the abdominal testicles some tubular cells were damaged already at 20 days of age, i. e. when the temperature difference between the testicles probably is quite small.In the abdominal testicles the pathological changes of the tubules precede those of the interstitium. The descended testicles of unilaterally cryptorchid rats were identical to testicles of normal control rats, and all the operated rats were fertile at adult age.

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