Abstract
The title compound, C18H30N2O5S, was synthesized by the reaction of tert-butyl 2-(isobutylamino)ethylcarbamate with p-methoxyphenylsulfonyl chloride. In the molecule, two intramolecular C—H⋯O hydrogen bonds are observed. In the crystal, molecules are linked by N—H⋯O hydrogen bonds involving the imino group N atom and the ester group O atom into chains running parallel to the b axis. The chains are further connected by C—H⋯O hydrogen bonds, forming layers parallel to the bc plane.
Highlights
The chains are further connected by C—H O hydrogen bonds, forming layers parallel to the bc plane
As a part of our ongoing project aimed at the development of potential HIV-1 protease inhibitors (Surleraux et al, 2005; Ghosh et al, 2006, 2011; Guo et al, 2010), we have synthesized the title compound and report its crystal structure
The molecular structure of the title compound, showing displacement ellipsoids drawn at the 30% probability level
Summary
R factor = 0.034; wR factor = 0.089; data-to-parameter ratio = 14.9. The title compound, C18H30N2O5S, was synthesized by the reaction of tert-butyl 2-(isobutylamino)ethylcarbamate with pmethoxyphenylsulfonyl chloride. Two intramolecular C—H O hydrogen bonds are observed. Molecules are linked by N—H O hydrogen bonds involving the imino group N atom and the ester group O atom into chains running parallel to the b axis. The chains are further connected by C—H O hydrogen bonds, forming layers parallel to the bc plane
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