Terpolymers Composed of Ethyl Acrylate, Methoxypolyethyleneglycol Methacrylate and Methoxypolypropyleneglycol Methacrylate as Pressure Sensitive Adhesives and their Blood Compatibility

Abstract

Terpolymers composed of ethyl acrylate (EA), methoxypolyethyleneglycol methacrylate (MPEGMA) and methoxypolypropyleneglycol methacrylate (MPPGMA) were synthesized by the photopolymerization technique. The high molecular mobilities for these terpolymers were shown by dynamic contact angle and adhesion tension measurement. The 180-degree peel strength and probe tack for pressure sensitive adhesives (PSA) made of these terpolymers were good but the holding power was not enough to apply them as PSAs. It was found that these terpolymers should be modified to obtain high holding power. The blood compatibility of these terpolymers was also investigated. It was found that they had a significant blood compatibility. Thrombi were not observed on the terpolymer surface after immersion in blood while, on a polystyrene (PSt) surface, many blood clusters were observed. After immersion in platelet-rich plasma (PRP), a few adhered platelets were observed on terpolymer surface but they did not deform and maintained their spherical form, while many platelets were observed on polystyrene.