Abstract
Neoboutomannin A (1), a new degraded diterpenoid monomer, and 3α-acetyl-14α-hydroxytaraxan-19,28-olide (2), a new triterpenoid derivative, have been isolated from the stem bark of Neoboutonia macrocalyx Benth (Euphorbiaceae), together with the known compounds, 3-acetyl aleuritolic acid (3), 3β-acetoxy oleanolic acid (4), oleanolic acid (5), 3,3,4-tri-O-methylellagic acid (6), sitosterol 3-O-β-d-glucopyranoside (7) and sitosterol (8). Their structures were elucidated on the basis of spectral data and comparison with those present in the literature. The methanol extract of the stem bark of N. macrocalyx showed high toxicity to brine shrimp nauplii (LC50=0.6±0.05μg/mL) and low antifungal activity on Candida albicans and Mucus miehei. Compound 3 exhibited moderate toxicity to brine shrimp (LC50=10.0±0.9μg/mL) and compound 2 showed low antifungal activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
