Abstract
Recently, considerable research has been made on the development of bone tissue engineering (BTE) scaffolds to support cellular behaviors. Here, black phosphorus-incorporated poly(ε-caprolactone) and collagen (PCL/BP/Col) nanofiber matrices were designed and their potential as BTE scaffolds were explored. The PCL/BP/Col nanofiber matrices were fabricated successfully by electrospinning, showing that they were suitable for supporting cell growth. The PCL/BP/Col nanofiber matrices could promote not only initial attachment and proliferation, but also osteodifferentiation of preosteoblasts. In conclusion, PCL/BP/Col nanofiber matrices possess excellent biocompatibility and improve osteogenic differentiation. Therefore, the PCL/BP/Col nanofiber matrices can be a promising candidate as a scaffold for BTE.
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