Ternary mutual diffusion coefficients of aqueous {l-dopa (1) + β-CD (2)} solutions at T = 298.15 K

Abstract

Ternary mutual diffusion coefficients (D11, D22, D12 and D21) measured by the Taylor dispersion method are reported for aqueous solutions of {levodopa (l-dopa)+β-cyclodextrin (β-CD)} solutions at T=298.15K and concentrations up to 0.007mol·dm−3. Significant effects on the diffusion were observed, suggesting interactions between this carbohydrate and l-dopa. Support for this came from 1H NMR spectroscopy, which shows that these effects are due to formation of 1:1 (β-CD:l-dopa) complexes.