Abstract
The present work focused on the assembly of 2-((2-(4-chlorophenylamino)phenylimino)methyl)-6-methoxyphenol as primary ligand (VBL) and bidentate nitrogen donors, namely 2,2′-bipyridyl (L1), 1,10-phenanthroline (L2), and ethylenediamine (L3) as secondary ligands with Cu(II) ion. The synthesized compounds were well characterized by different spectral techniques. From the spectral data, square pyramidal geometry is obtained around Cu(II) center. Compounds so prepared have been subjected to interactions with calf thymus DNA and supercoiled pBR322 plasmid DNA. These studies revealed that these complexes have good interacting property. Anticancer activity to the HeLa (human cervical cancer) and MCF-7 (breast cancer) cell lines showed substantial cytotoxic effect. The compounds were screened for in vitro antibacterial activity, and the results showed that the complexes exhibited good activity against various pathogens.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
