Teratogenicity: a mechanism based short review on common teratogenic agents

Abstract

Teratogenicity or reproductive and developmental toxicity has increasingly been recognized as a most important part of overall toxicology. Each compound has its own unique toxicological profile and mechanism of teratogenicity. The present view-point was to explore and review the teratogenic mechanism and common teratogenic effects of teratogenic compounds, biological agents and physical agents. Every year millions of different chemicals are produced and used in the world which contaminate environment and consequently are exposed to human. Many of these chemicals have ability to penetrate into human tissue and developing foetus, negatively impacting the reproductive health of human. Many of the teratogenic effects occur because of biological and physical factors like infection and radiation respectively.