Abstract

The slope of the sarcomere length-tension relation in cardiac papillary muscle suggests length-dependent activation of the contractile system (1). However, there are no data on the effect of inotropic interventions on this curve. Only muscle length-tension curves are available, which give conflicting results (1,2,3). The purpose of the present study was to examine the effect of varied calcium concentrations on the sarcomere length-tension relationship, using laser diffraction techniques.

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