Tenosynovial giant cell tumors as accidental findings after episodes of distortion of the ankle: two case reports.

Christian Illian,Markus Schofer,Ludger W Poll,Horst-Rainer Kortmann,Hans Otto Künstler

doi:10.1186/1752-1947-3-9331

Christian Illian, Markus Schofer + Show 3 more

Open Access

https://doi.org/10.1186/1752-1947-3-9331

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Abstract

IntroductionTenosynovial giant cell tumors are benign tumors of uncertain pathogenesis. They occur in the joints, tendons and synovial bursas. Due to a high recurrence rate of up to 50%, some authors call a giant cell tumor a semimalignant tumor. To date, less than 10 cases of tenosynovial giant cell tumor of the ankle have been published in the international medical literature.Case presentationIn this case report, we present two patients with localized tumors that were detected accidentally after the occurrence of ankle sprains with persisting pain in the joint. The tumors were resected by open marginal surgery and regular follow-up examinations were carried out.ConclusionsWe present an unusual occurrence of a tumor along with a possible follow-up strategy, which has not been previously discussed in the international literature.

Highlights

Tenosynovial giant cell tumors are benign tumors of uncertain pathogenesis
Case presentation: In this case report, we present two patients with localized tumors that were detected accidentally after the occurrence of ankle sprains with persisting pain in the joint
The tumors were resected by open marginal surgery and regular follow-up examinations were carried out

Summary

Introduction

A tenosynovial giant cell tumor (TGCT) is a benign tumor of uncertain pathogenesis It occurs in the joints, tendons and synovial bursas. A magnetic resonance imaging (MRI) scan revealed an unknown but well-circumscribed localized tumor at the ventral part of the ankle, coupled with focal bulging and erosion of the tibia and talus (Figure 1). Investigations three, six, 12, and 24, as well as the MRI scan conducted 24 months after surgery, showed no recurrence of the TGCT (Figure 3). To this day the patient is free of any symptoms. Si(Fnaaigrggriuatotrwael)eT1ll1d-welienigehated gspiaint-eccehllotuMmRoI roaf nthteerrioigrhtoanthkeleasnhkolewSagittal T1-weighted spin-echo MRI of the right ankle showing a well delineated giant cell tumor anterior to the ankle (arrow). MFiagcurroesc2opic and histological images of the TGCT Macroscopic and histological images of the TGCT. (A) A macroscopic image of the tumor after resection. (B) Histological findings using hematoxylin and eosin staining of a giant cell

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Discussion

Conclusions