Abstract
Research Article| May 01 2021 Tenofovir Alafenamide to Prevent Perinatal HBV Infection AAP Grand Rounds (2021) 45 (5): 59. https://doi.org/10.1542/gr.45-5-59 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Tenofovir Alafenamide to Prevent Perinatal HBV Infection. AAP Grand Rounds May 2021; 45 (5): 59. https://doi.org/10.1542/gr.45-5-59 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search nav search search input Search input auto suggest search filter All PublicationsAll JournalsAAP Grand RoundsPediatricsHospital PediatricsPediatrics In ReviewNeoReviewsAAP NewsAll AAP Sites Search Advanced Search Topics: hepatitis b, perinatal period, tenofovir alafenamide Source: Zeng Q-L, Yu Z-J, Ji F, et al. Tenofovir alafenamide to prevent perinatal hepatitis B transmission: a multicenter, prospective, observational study [published online ahead of print January 4, 2021]. Clin Infect Dis. 2021;ciaa1939. doi: https://doi.org/10.1093/cid/ciaa1939Google Scholar Investigators from multiple institutions in China conducted a prospective study to assess the safety and effectiveness of tenofovir alafenamide fumarate (TAF), an alternative to tenofovir disoproxil fumarate (TDF), in preventing mother-to-child perinatal transmission of hepatitis B virus (HBV). Study participants were pregnant women with HBV DNA levels >200,000 IU/mL who were assigned on a 1:1 basis to receive TAF or TDF during pregnancy. In addition to demographic information, HBeAg status and HBV DNA levels were collected at baseline. Data on adverse events were collected, and maternal levels of alanine aminotransferase (ALT) and hepatitis B status were obtained when the women gave birth and... You do not currently have access to this content.
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