Abstract

Introduction Descriptive models of basal ganglia operation have seen a recent increase in interest from the classical idea of direct and indirect pathways towards a more feedback-oriented view of statistic optimality [1]. These new views may prove to be valuable in explaining and finding new treatments for common basal ganglia disorders such as Parkinson's disease beyond current techniques of pure symptom fighting through widespread deep brain stimulation or chemical regulators for increasing tonic levels of dopamine.

Highlights

  • Eighteenth Annual Computational Neuroscience Meeting: CNS*2009 Don H Johnson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1471-2202-10-S1-info.pdf

  • Descriptive models of basal ganglia operation have seen a recent increase in interest from the classical idea of direct and indirect pathways towards a more feedback-oriented view of statistic optimality [1]

  • These new views may prove to be valuable in explaining and finding new treatments for common basal ganglia disorders such as Parkinson's disease beyond current techniques of pure symptom fighting through widespread deep brain stimulation or chemical regulators for increasing tonic levels of dopamine

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Summary

Introduction

Descriptive models of basal ganglia operation have seen a recent increase in interest from the classical idea of direct and indirect pathways towards a more feedback-oriented view of statistic optimality [1]. Tending the source of parkinsonism through deep brain microstimulation Simon M Vogt*, Felix Njap and Ulrich G Hofmann Address: Institute for Signal Processing, University of Lübeck, Lübeck, D-23562, Germany Email: Simon M Vogt* - vogt@isip.uni-luebeck.de * Corresponding author

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