Abstract
Carboxyhemoglobin concentrations ([COHb]) were measured in 15 subjects by analysis of alveolar air samples collected at two-hour intervals during waking hours on seven consecutive days. Overall mean values were 3.80% COHb for five cigarette smokers and 1.64% COHb for ten nonsmokers. Analysis of the results indicates that long-term average [COHb] can be estimated with fair reliability from two or more instantaneous samples for each subject. This technique may be useful in estimating chronic carbon monoxide (CO) exposures for epidemiologic studies.
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