Temporal dynamics of surround suppression in the corticogeniculate feedback pathway

Abstract

Event Abstract Back to Event Temporal dynamics of surround suppression in the corticogeniculate feedback pathway Neurons in the early visual system respond in a selective manner to stimuli that vary in size. Within the lateral geniculate nucleus of the thalamus (LGN), neurons display a similar time course of excitation to stimuli restricted to the classical receptive field and suppression to stimuli that extend into the extra-classical surround. Given the implication that surround suppression arises from feedforward retinal mechanisms, we explored the temporal dynamics of suppression across distinct populations of neurons in primary visual cortex (V1), including those that provide feedback projections to the LGN. To do so, we measured neuronal responses to drifting sinusoidal gratings optimized for preferred orientation, direction, spatial and temporal frequency in alert monkeys performing a fixation task for juice rewards. Gratings varied in size (diameter) between 0.2 and 10 degrees. We then compared the temporal dynamics of visual responses to stimuli that varied in size and estimated the timing and magnitude of suppression. Our results show that different classes of corticogeniculate neurons display different temporal profiles for surround suppression, indicating circuit-specific mechanisms for the generation of suppression in the corticogeniculate feedback pathway. This work was supported by NIH grants EY013588 and EY12576; and the McKnight Foundation. Conference: Computational and systems neuroscience 2009, Salt Lake City, UT, United States, 26 Feb - 3 Mar, 2009. Presentation Type: Poster Presentation Topic: Poster Presentations Citation: (2009). Temporal dynamics of surround suppression in the corticogeniculate feedback pathway. Front. Syst. Neurosci. Conference Abstract: Computational and systems neuroscience 2009. doi: 10.3389/conf.neuro.06.2009.03.077 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 30 Jan 2009; Published Online: 30 Jan 2009. Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Google Google Scholar PubMed Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.