Abstract

WCN 2013 No: 2441 Topic: 7 Neuromuscular disorders The follow-up of the patients with GBS treated with plasmapheresis A. Kuqo, H.V. Doci, L. Buda, M.H. Papajani, S. Grabova, F. Myslimi, A.A. Quka, J. Kruja. Neurology, QSUT, Tirana, Albania Background: GBS is an acute polyneuropathy, a disorder affecting the peripheral nervous system. It can cause life-threatening complications, in particular if the respiratory muscles are affected or if there is autonomic nervous system involvement. The disease is usually triggered by an infection. Treatment consists of attempting to reduce the body's attack on the nervous system by plasmapheresis. Objective: To evaluate the efficacy of PEX in GBS patients. Methods: In our prospective study a group of 17 patients with GBS was evaluated before, immediately after PEX and 1 year later. The evaluation was made using the Hughes functional grading scale for GBS (from Hughes et al., Lancet 1978). Results: We have evaluated the 17 patients. We have found an improvement in 14/17(82.35%) patients immediately after and 1 year after the PEX treatment. We haven't found an improvement in 3/17 patients. In 4 patients the progression of the neurological signs was stopped immediately after the first PEX procedure and in these patients we have found better results. We have found good results even in patients who require assisted ventilation (score 5 of Hughes functional grading scale for GBS). 3/17(17.64%) patients had an improvement even they haven't made all the PEX procedure because of complications. Conclusions: The PEX treatment in GBS patients is efficient. The improvement consisted of good clinical outcome. In some cases the progression of clinical signs was stopped even after only one procedure. doi:10.1016/j.jns.2013.07.1663 Abstract WCN 2013 No: 1004 Topic: 7 Neuromuscular disorders Temporal cortical damage as a prognostic marker in ALS (amyotrophic lateral sclerosis) WCN 2013 No: 1004 Topic: 7 Neuromuscular disorders Temporal cortical damage as a prognostic marker in ALS (amyotrophic lateral sclerosis) M. Albuquerque, H.M.T. Andrade, F.P.G. Bergo, M.C. FrancaJunior, A. Nucci. Neurology, Universidade Estadual de Campinas, Campinas, Brazil; Neurology, Universidade Estadual de Campinas, Campinas, Brazil; Computer Engineering, Universidade Estadual de Campinas,

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