Abstract
Thyroid cancer is the most common type of endocrine cancer. We aimed to determine the incidence rates of thyroid cancer across a 10-year period (2004-2013) in Golestan, Iran. We obtained the thyroid cancer data from Golestan Population-Based Cancer Registry (GPCR). Age-standardized incidence rates (ASR) were calculated and reported per 100000 person-years. The Joinpoint software was used to assess time trends, and average annual percent changes (AAPCs) and their corresponding 95% confidence intervals (CIs) were reported. Of 326 registered patients, 83 (25.5%) were men and 243 (74.5%) were women. The mean age was 51.3 and 42.6 years for males and females, respectively. Overall, the ASR of thyroid cancer was 2.2 per 100000 person-year (AAPC = 2.76; 95% CI: -3.68 to 9.64). The test of co-incidence showed a statistically significant difference in the incidence of thyroid cancer between men (1.3) and women (3.2) (P < 0.001). According to our results, the ASR of thyroid cancer in western parts of Golestan is higher, including Gorgan and Aliabad cities. Increasing trends in incidence rates of thyroid cancer were found in the Golestan province during the study period, especially in women. We found significantly higher rates of thyroid cancer in women. Geographical diversities were seen in incidence rates of thyroid cancer in the Golestan province. Our results may be helpful for designing further researches to investigate the epidemiological aspects of thyroid cancer in the Golestan province.
Highlights
Cancer is a major cause of death worldwide, with an estimated 9.6 million deaths in 2018.1 According to the International Agency for Research on Cancer (IARC), there are 110 115 new cases of cancer in Iran, annually.[1]
Thyroid cancer is the fifth cancer among women around the world, and the fourth common cancer in Iran according to global cancer statistics 2018.1 Incidence rates are higher in women than men, children than adults, and young adults than the older population.[2]
Our findings showed that 326 (1.6%) of the total 19 807 new cancer cases registered in Golestan Population-Based Cancer Registry (GPCR) from 2004 to 2013 were thyroid cancer
Summary
Cancer is a major cause of death worldwide, with an estimated 9.6 million deaths in 2018.1 According to the International Agency for Research on Cancer (IARC), there are 110 115 new cases of cancer in Iran, annually.[1]. Thyroid cancer is the fifth cancer among women around the world, and the fourth common cancer in Iran according to global cancer statistics 2018.1 Incidence rates are higher in women than men, children than adults, and young adults than the older population.[2] Previous studies have shown that thyroid cancer incidence rates are different in areas with different ethnic and geographical characteristics.[10] According to Globocan 2012, the agestandardized incidence rate (ASR) of thyroid cancer was 7.3 and 3.0 in more developed areas and less developed areas, respectively.[11] The ASR of thyroid cancer was 10.2 and 3.1 per 100 000 person-years for females and males worldwide, respectively.[1]. We aimed to determine the incidence rates of thyroid cancer across a 10-year period (2004-2013) in Golestan, Iran.
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