Template-Based Synthesis of Nanoporous Hydroxyapatite

E Salimi,M Anbia,J Javadpour

doi:10.5402/2012/960915

E Salimi, M Anbia + Show 1 more

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https://doi.org/10.5402/2012/960915

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Journal: ISRN Ceramics	Publication Date: Oct 17, 2012
Citations: 29	License type: CC BY 3.0

Affiliation: Iran University of Science and Technology

Abstract

Hydroxyapatite (HAp) particles, a potential starting material for bone substitutes, with nanopores were synthesized in the presence of cetyltrimethylammonium bromide (CTAB) and P123 as cationic and nonionic surfactants as the structuring units. Effect of nonionic surfactant concentration on surface areas is also investigated. Based on N2 adsorption-desorption isotherms investigation, surface area increased up to 50 m2/g by using P123 and 147 m2/g by using CTAB as porosity agent. Pore structure remained even after the removal of surfactant and calcinations at 400°C.

Highlights

Hydroxyapatite, Ca10 (PO4 )6 (OH)2, is a form of bioceramics material [1]
HA can be used as drug delivery agent, such as for the delivery of antitumor agents and antibodies in the treatment of osteomyelitis: a bone infection that is often treated by excision of necrotic tissue and irrigation of the wound [4]
In a successful synthesis run to yield only single-phase (Ca10 (PO4 )6 (OH)2, HA), 5.91 gr diammonium hydrogen phosphate ((NH4 )2 HPO4 ) and 5 gr cetyltrimethylammonium bromide (CTAB) were dissolved in mL deionized water at room temperature with stirring for hr pH that was adjusted to 10 using sodium hydroxide

Summary

Introduction

Hydroxyapatite, Ca10 (PO4 ) (OH) (denoted as HA), is a form of bioceramics material [1]. It is chemically similar to bones and hard tissues found in humans. Surfactant-templated mesoporous materials have some specific features such as high surface areas and high adsorption capacities including the uniformity and periodicity of tunable mesopores [9,10,11], which are widely applicable to adsorbents and catalytic supports [12,13,14,15,16,17,18]. We attempt to achieve the direct crystallization of mesoporous hydroxyapatite by chemical precipitation method using CTAB and P123 as structure-directing agents.

Experimental

Results and Discussion

Conclusions