Abstract
A simulation, using the implicit alternating direction finite difference method, has been made for the treatment of malignant tumors by local hyperthermia. The simulation is three dimensional in temperature, two spatial coordinates and the time coordinate being considered. The results indicate the effects of varying thermophysical properties, varying blood perfusion rates, varying the microwave heating power and varying the area of the microwave beam. The small changes in the properties and blood perfusion rates which are expected in the tissue are shown to have little effect on the thermal fields whereas the power and the heat flux are shown to be the parameters upon which the treatment will depend most heavily. In addition the effect of nearby physiological structures such as arteries and bone are included. The temperature fields are found to be weakly dependent upon the increased perfusion rates encountered in the arteries and only when the perfusion rate in the artery exceeds that in the tissue by an order of magnitude or more is it significant. Similar dependence is found for bone where the thermal diffusivity is much less than in the tissue.
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