Abstract
The thermal and UV-light sensitivity of a laboratory-adapted rubella virus (strain Wright) was assayed quantitatively and by electron microscopic observation. As judged by the appearence of cytopathic effects in cultures of African green monkey kidney cells (Vero) and/or by the presence of rubella virus particles in electron microscopic preparations, infectivity was found to withstand inactivation temperatures up to 70° C for 30 minutes. Infectious tissue culture fluid treated by UV-irradiation for 60 minutes also produced cytopathic effects in Vero cells. Ultrastructurally, however, only a few rubella virus-like particles could be detected. Virus suspensions filtered through 0.22 μ membrane filters prior to heat-or UV-treatment failed to reveal residual infectivity. Some of the possible mechanisms responsible for this marked thermal and UV-resistance of the rubella virus strain used are discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
