Abstract
Pituitary tumours account for about 15% of all intracranial neoplasms, and clinically evident local invasion takes place in 35–40% of cases. 1 Sellman WR Laws ER Scheithauer BW Carpenter SM The occurrence of dural invasion in pituitary adenomas. J Neurosurgery. 1986; 64: 402-407 Crossref PubMed Scopus (236) Google Scholar Pituitary carcinoma is tumour tissue that is not contiguous with the pituitary tissues or is found in other extracranial sites. The disorder is rare (accounting for about 0·1% of pituitary tumours), rapidly progressive, and largely unresponsive to current combination treatment of surgery, radiation, and systemic chemotherapy. 2 Kaltsas GA Nomikos P Kontogeorgos G et al. Diagnosis and management of pituitary carcinoma. J Clin Endocrinol Metab. 2005; 90: 3089-3099 Crossref PubMed Scopus (260) Google Scholar , 3 Ragel BT Couldwell WT Pituitary carcinoma: a review of the literature. Neurosurg Focus. 2004; 16: E7 Crossref PubMed Scopus (151) Google Scholar Consequently, most patients die within 1 year of diagnosis. Here, we report a case of pituitary carcinoma treated with temozolomide.
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