Abstract

A syndrome of eosinophilia with systemic symptoms associated with ingestion of L-tryptophan was first described in late 1989.1 By Aug. 24, 1990, 1536 cases of eosinophilia-myalgia syndrome (EMS) had been reported to the Centers for Disease Control.2 The criteria for diagnosis are an eosinophil count greater than 1000 cells/rnrn,3 generalized myalgias, and absence of infection or neoplasm to account for the clinical symptoms. The cutaneous manifestations include a diffuse, pruritic, morbilliform eruption; urticaria; angioedema; sclerodermatous changes; and hair 10ss.3 We report a patient with EMS who had a severe, persistent, telogen effluvium.

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