Abstract
To study outcomes and functional results of a telescopic straight ileo-anal anastomosis. Thirty-six mongrel dogs were submitted to total proctocolectomy and telescopic straight ileo-anal anastomosis (ileal mucosa-submucosa pulled-through the rectal cuff). They were divided in 3 groups, sacrificed after one, two or eight weeks after the initial procedure. Gross and microscopic (degree of cooptation and signs of ischemia) aspects of the anastomosis, as well, the aspect of defecation were analyzed. On microscopy all anastomosis analysed showed a continuous epithelial line and were considered good. After two-months no signs of ischemia were identified. Defecation aspect has considerably changed during the study, so no dogs presented solid defecation within the first two weeks, whereas 80% of dogs presented solid stools after two months. Telescopic ileo-anal anastomosis is a safe alternative and may provide good functional results after some small period of time.
Highlights
Ileal pouch anal anastomosis (IPAA) has become the standard of care for reconstruction after total proctocolectomy for ulcerative colitis (UC) or familial polyposis
Six dogs died before one week and were not considered for analysis
Signs of ischemia were identified by microscopy in 4/10, and 2/10 dogs of groups 1 and 2 respectively
Summary
Ileal pouch anal anastomosis (IPAA) has become the standard of care for reconstruction after total proctocolectomy for ulcerative colitis (UC) or familial polyposis. IPAA is associated with early and late complications. Anastomosis dehiscence, abscess and pelvic septicemia, and fistulae are not uncommon and total rate of early complications may reach 43.7%1,2. The rate ranges from 3.5 to 15%, and the main causes are: unrecognized Crohns disease, persistent pelvis sepsis, mediocre functional results, desmoids tumors, and tumor recurrence[7,8]. To reduce this failure rate, several teams have developed techniques to salvage the reservoir
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