Abstract
This work attempts to integrate questions posed by research on processes of technological change with that on the relative cohesiveness of national institutional economies, or national systems of innovation. Studying the processes behind the use of biotechnology-genetic engineering to make the pharmaceutical human growth hormone as occurred in Sweden and the United States-provides a rich comparative study. A historical understanding of specific science-based technologies provides possibilities to address more general models and theories about the nature of technological change in political Economics of nations.
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