Abstract
The tests used to measure the neuromuscular junction function in children are repetitive nerve stimulation (RNS) and single-fibre electromyography (SFEMG). The physiological changes which explain abnormalities in RNS are covered in this chapter as are those affecting jitter measurement when measured by SFEMG. Practical considerations of how to perform RNS in children are discussed, along with the reasons for using SFEMG in preference to RNS and the need to use stimulation techniques. Controversies concerning so-called stimulated SFEMG including needle selection, filter settings, and the origin of the potentials that are being sampled are all discussed. The term stimulated potential analysis using concentric needle electrodes (SPACE) is introduced to divert most if not all of these criticisms. Derivation of normative data from previous studies is described as well as the use of e-norm methodology on laboratory data. The chapter concludes with practical measures of how to analyse the data collected and reference is made to the cross-correlation technique for determining abnormalities.
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