Abstract
PurposeThree‐dimensional (3D) dosimetry is a necessity to validate patient‐specific treatment plans in particle therapy as well as to facilitate the development of novel treatment modalities. Therefore, a vendor‐agnostic water phantom was developed and verified to measure high resolution 3D dose distributions.MethodsThe system was experimentally validated at the Marburger Ionenstrahl‐Therapiezentrum using two ionization chamber array detectors (PTW Octavius 1500XDR and 1000P) with 150.68 MeV proton and 285.35 MeV/u 12C beams. The dose distribution of several monoenergetic and complex scanned fields were measured with different step sizes to assess the reproducibility, absolute positioning accuracy, and general performance of the system.ResultsThe developed system was successfully validated and used to automatically measure high resolution 3D dose distributions. The reproducibility in depth was better than ±25 micron. The roll and tilt uncertainty of the detector was estimated to be smaller than ±3 mrad.ConclusionsThe presented system performed fully automated, high resolution 3D dosimetry, suitable for the validation of complex radiation fields in particle therapy. The measurement quality is comparable to commercially available systems.
Highlights
State‐of‐the‐art particle therapy can deliver highly conformal dose distributions to target volumes while sparing healthy tissues due to their advantageous inverse depth dose distributions and increased biological effectiveness compared to other forms of external radiation therapy.[1]
We describe the current iteration of WERNER, optimized for the use at MIT and for the PTW 2D ionization chamber arrays OCTAVIUS 1500XDR and 1000P
Validation of the 3D dosimetry capabilities of the system with ion beams was performed at MIT using 150.68 MeV proton and 285.35 MeV/u 12C beams with the PTW 1500XDR and the PTW 1000P
Summary
State‐of‐the‐art particle therapy can deliver highly conformal dose distributions to target volumes while sparing healthy tissues due to their advantageous inverse depth dose distributions and increased biological effectiveness compared to other forms of external radiation therapy.[1]. Even though the stopping power of materials such as water‐equivalent plastics are comparable to water, nuclear interactions of heavier ions, such as carbon, and scattering of light ions, such as protons, will be different in these materials and will have detrimental effects on the comparability of the measurement outcome.[7].
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