Technical note: Unequivocal identification of 5-methoxy-DiPT with NOESY NMR and GC-IRD

Abstract

The need for new analytical methods to differentiate isomers and closely related compounds have become increasingly important due to the fast evolution of new psychoactive substances. 2D NMR and GC-IR spectroscopies are promising techniques due to their capabilities to differentiate isomers. This case study highlights specifically the use of Nuclear Overhauser Effect Spectroscopy (NOESY) and solid deposition GC-IRD in the unequivocal identification of 5-methoxy-DiPT, a tryptamine analogue.