Abstract
In magnetic resonance (MR)-guided thermal therapy, respiratory motion can cause a significant temperature error in MR thermometry and reduce the efficiency of the treatment. A respiratory motion simulator is necessary for the development of new MR imaging (MRI) and motion compensation techniques. The purpose of this study is to develop a low-cost and simple MR-compatible respiratory motion simulator to support proof-of-concept studies of MR monitoring approaches with respiratory-induced abdominal organ motion. The phantom motion system integrates pneumatic control via an actuator subsystem located outside the MRI and coupled via plastic tubing to a compressible bag for distention and retraction within the MRI safe motion subsystem and phantom positioned within the MRI scanner. Performance of the respiratory motion simulator was evaluated with a real-time gradient echo MRI pulse sequence. The motion simulator can produce respiratory rates in the range of 8-16 breaths/min. Our experiments showed the consistent periodic motion of the phantom during MRI acquisition in the range of 3.7-9mm with 16 breaths/min. The operation of the simulator did not cause interference with MRI acquisition. In this study, we have demonstrated the ability of the motion simulator to generate controlled respiratory motion of a phantom. The low-cost MR-compatible respiratory motion simulator can be easily constructed from off-the-shelf and 3D-printed parts based on open-source 3D models and instructions. This could lower the barriers to the development of new MRI techniques with motion compensation.
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