Abstract

PurposeCyclotron‐based pencil beam scanning (PBS) proton machines represent nowadays the majority and most affordable choice for proton therapy facilities, however, their representation in Monte Carlo (MC) codes is more complex than passively scattered proton system‐ or synchrotron‐based PBS machines. This is because degraders are used to decrease the energy from the cyclotron maximum energy to the desired energy, resulting in a unique spot size, divergence, and energy spread depending on the amount of degradation. This manuscript outlines a generalized methodology to characterize a cyclotron‐based PBS machine in a general‐purpose MC code. The code can then be used to generate clinically relevant plans starting from commercial TPS plans.MethodsThe described beam is produced at the Provision Proton Therapy Center (Knoxville, TN, USA) using a cyclotron‐based IBA Proteus Plus equipment. We characterized the Provision beam in the MC FLUKA using the experimental commissioning data. The code was then validated using experimental data in water phantoms for single pencil beams and larger irregular fields. Comparisons with RayStation TPS plans are also presented.ResultsComparisons of experimental, simulated, and planned dose depositions in water plans show that same doses are calculated by both programs inside the target areas, while penumbrae differences are found at the field edges. These differences are lower for the MC, with a γ(3%–3 mm) index never below 95%.ConclusionsExtensive explanations on how MC codes can be adapted to simulate cyclotron‐based scanning proton machines are given with the aim of using the MC as a TPS verification tool to check and improve clinical plans. For all the tested cases, we showed that dose differences with experimental data are lower for the MC than TPS, implying that the created FLUKA beam model is better able to describe the experimental beam.

Highlights

  • An increasing number of particle therapy facilities are nowadays functional with active pencil beam scanning (PBS) replacing passive scattered beam systems

  • The treatment planning systems (TPS) and Monte Carlo (MC) dose were scored in the entire phantom, while for the comparison with the experimental dose, dose maps were recorded at three depths in water using the Lynx and MatrixPT detectors

  • We outlined the steps to create a cyclotron accelerated PBS beam model in FLUKA starting from the commissioning measured data and Monitor units (MU) calibration data available in the TPS

Read more

Summary

Introduction

An increasing number of particle therapy facilities are nowadays functional with active pencil beam scanning (PBS) replacing passive scattered beam systems. Monte Carlo simulations are a valuable instrument to obtain more reliable dose maps.[6,7] General purpose Monte Carlo (MC)-based codes are able to accurately calculate the dose outside high-dose regions, providing better estimate of the dose to the healthy tissues and can provide dose deposited by various particles separately Secondary particles such as neutrons, light ions, delta-rays, x rays, and gamma photons can be tracked and by scoring them separately we can assess their radiobiological impact through LET,[8] RBE9 or DNA damage conversion,[10,11] which might be important in assessing the quality of a particle treatment

Methods
Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call