Abstract

To evaluate the association between facial pain and maxillofacial scintigraphy. A total of 117 patients with idiopathic facial pain (IFP) (88% females; average age = 46.7 years) underwent 99mTc-MDP scans, as did 32 age-matched controls. Pearson χ(2) analysis was used to determine associations. Of subject quadrants, 63% were painful (average duration: 5.4 years); 79% of painful quadrants had positive 99mTc-MDP scans, i.e., "hot spots," significantly different from 13% in nonpainful quadrants (P < .0001). Five percent of controls had quadrants with hot spots; the proportion of hot spots in subjects versus controls was significantly different (P < .0001). No difference was found between pain-free quadrants in subjects and controls (P = .0688). A positive 99mTc-MDP scan is strongly correlated with the location of pain in IFP, and patients with IFP have significantly more hot spots than controls, suggesting that pain in some IFP is associated with or caused by cancellous bone disease.

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