Abstract

Correspondence: He D’Arceuil Department of Radiology, H0100, Nuclear Medicine Imaging Laboratory, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94303, USA Tel +1 650 725 1147 email helen@nmr.mgh.harvard.edu Abstract: Technetium-99m tetrofosmin is a radioactive tracer which is designed for myocardial perfusion imaging. Differential tracer uptake allows discrimination between normal and ischemic myocardium. Technetium-99m tetrofosmin has shown excellent utility as a safe, cost-effective, and technically sound agent for use in the diagnosis of coronary artery disease. This paper provides an overview of the available literature on clinical applications of technetium-99m tetrofosmin, and shows how this tracer has gained widespread acceptance as a diagnostic aid since its inception approximately 17 years ago. The various cardiac imaging modalities and imaging protocols which have employed this agent are also briefly reviewed.

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