Abstract
AbstractPurpose To evaluate tear break‐up time (BUT) with repeated higher order wavefront aberrations (HOA) measurements in adult patients with Meibomian Gland Dysfunction(MGD).Methods Wavefront aberrations up to the sixth order for a 4‐mm pupil were measured in 10 normal subjects (Group 1) and 10 patients with severe MGD (Group 2) with corneal involvement, using the IRX3 (Imagine Eyes, Orsay, France) Hartmann‐Shack (H‐S) aberrometer. The aberrometry was performed once every second for up to 20 seconds. HOA measurements were performed 3 times in a row. HOA variations were compared with the BUT by the conventional fluorescein method(CFM).Results There was an excellent correlation between the HOA variation and the BUT recorded by the CFM in both groups. There was also an excellent reproducibility of the HOA measurements in all patients. BUT was significantly decreased (P<0.005) in all patients in Group 2 compared to the normal tests subjects (Group 1).Conclusion Studying the HOA variation is a valuable method for evaluatingboth the quality visionand the BUT in patients with MGD and evaporative Dry Eye.The IRX3 H‐S aberrometer can be used for an objective and reproducible assessment of the BUT in the follow‐up of patients with severe MGD.
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