Year-end Sale % OFF 
Abstract
A 4-year-old-girl with Rett syndrome (RS) presented with drug-resistant epilepsy since 4 years of age. Her video-EEG captured rhythmic hand tapping with bilateral central spike-and-waves (figure and video 1). Characteristic EEG features in RS include prominent central rhythmic theta activity during wakefulness and needle-like central spikes evoked by contralateral passive finger-tapping. These central spikes may represent exaggerated somatosensory evoked potential secondary to the presence of hyperexcitable motor and sensory cortices. Reflex seizures (focal and atonic) provoked by rhythmic hand pressure have been described in 2 children with RS.1 In contrast, hand clapping has also been reported to suppress continuous centrotemporal spikes.2 Thus, the clinical significance of these provoked central spikes is unclear.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
