Abstract
A 28-year-old man had experienced binocular diplopia for the last 2 months. Around the same time, he noticed mostly nocturnal polyuria and polydipsia and eventually was diagnosed with diabetes insipidus. Extraocular motility testing demonstrated jerky convergence movements on an attempted upgaze and mild lid retraction (video 1). Urgent MRI of the brain revealed a large mass in the dorsal midbrain region, which was also compressing the hypothalamus (figure). The lesion was biopsied and a diagnosis of primary intracranial germinoma arising from pineal tissue was made. Treatment with low-dose radiotherapy commenced. Characteristic clinical features of convergence retraction nystagmus in this case allowed rapid localization of the lesion, its diagnosis, and eventually treatment.1
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
