Abstract

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Highlights

  • Teaching Case 5-2018: Integrated diagnosis of neuroinflammatory lesions that acute disseminated encephalomyelitis (ADEM) represents a clinical syndrome that may be initiated by different pathogenetic triggers

  • Neuropathology is characterized by perivenous demyelination and inflammatory infiltrates that are dominated by T-cells, variable amounts of B-cells, and abundant macrophages and activated microglia [3]

  • Teaching Case 5-2018: Integrated diagnosis of neuroinflammatory lesions that ADEM represents a clinical syndrome that may be initiated by different pathogenetic triggers

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Summary

Introduction

Teaching Case 5-2018: Integrated diagnosis of neuroinflammatory lesions that ADEM represents a clinical syndrome that may be initiated by different pathogenetic triggers. ADEM is a severe acute demyelinating disease with an annual incidence of 0.1 – 0.7 cases per 100.000 [1, 2].

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