Abstract
Background: Clinical correlates and prognostic significance of coronary artery calcifications (CAC) in women undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) remain unclear. Objectives: We sought to investigate the clinical correlates and prognostic impact of CAC in women undergoing PCI with DES. Methods: We pooled patient-level data of female participants from 26 randomized trials of DES. Study population was categorized according to the presence of moderate or severe versus mild or none target lesion CAC, assessed through coronary angiography. Co-primary endpoints of interest were the composite of death, myocardial infarction (MI) or target lesion revascularization (TLR) and death, MI or stent thrombosis (ST) at 3 years of follow-up. Results: Out of 11,557 women included in the pooled dataset, CAC status was available in 6,371 women. Of these, 1,622 (25.5%) had moderate or severe CAC. In fully adjusted models, independent correlates of CAC were age, hypertension, hyperc...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
