Abstract
Early and precise diagnosis of cutaneous T-cell lymphomas (CTCL) is a challenge. The identification of T-cell receptor (TCR) clonality plays an important part in the diagnostic process. Polymerase chain reaction (PCR)-based clonality assessment following the Biomed-2 protocol is an everyday gold standard method in the assessment of the T-cell receptor clonality. We aimed to assess the sensitivity and specificity of this diagnostic method, based on a complete dataset collected over a 5-year period from 2012 to 2017 in our specialized tertiary center.
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