Abstract

Brain scanning is an important tool in the diagnosis of intracranial disease. With Hg203 and Hg197 as chlormerodrin, the scans are nucleographically positive in a variety of intracranial abnormalities including meningioma, primary and metastatic cerebral neoplasia, cerebral infarct, and arteriovenous malformation. The purpose of this communication is to illustrate their positive quality, with use of a new scanning agent Tc99m-sodium pertechnetate. The tumor-to-brain ratio of Tc99m-pertechnetate in mouse ependymoma is 22, a value similar to that of the radiomercurial compounds (1). The availability of short-lived radionuclide generators in clinical nuclear medicine laboratories has been a significant advance in diagnostic brain scanning (2, 3). Because of the shorter physical half-life of these nuclides, larger doses can be administered to the patient achieving: 1. Greater counting rates, and thereby improved counting statistics 2. Faster scanning speeds, because of the improved counting rate 3. Reduced pa...

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