TBT 노출에 따른 돌돔, Oplegnathus fasciatus의 성장 및 혈액성분의 변화

Abstract

본 실험은 TBT에 노출된 돌돔의 성장 및 혈액학적 변동을 검토하기 위하여 실시하였다. 돌돔은 TBT 0, 1, 2, 4, <TEX>$8{\mu}g/L$</TEX> 농도에서 4주간 노출하였다. 돌돔의 성장은 <TEX>$8{\mu}g/L$</TEX> TBT 농도에서 유의한 감소를 나타냈다. RBC count, hematocrit 값, hemoglobin 농도, 혈청 glucose 농도는 <TEX>$8{\mu}g/L$</TEX> TBT 농도에서 유의한 감소를 나타낸 반면, 총 단백질 농도는 유의한 증가를 나타냈다. 또한 GOT 및 GPT 활성은 <TEX>$8{\mu}g/L$</TEX> TBT 농도에서 유의한 증가를 나타냈다. 따라서 해역에 TBT 농도 <TEX>$8{\mu}g/L$</TEX> 이상의 존재할 경우에는 돌돔의 성장 및 혈액학적 변동이 예상된다. Experiments were carried out to investigate the growth and hematological parameters of rock bream Oplegnathus fasciatus exposed to several different concentrations (0, 1, 2, 4, <TEX>$8{\mu}g/L$</TEX>) of tributyltin (TBT) for 4 weeks. Growth rate of the fish exposed to <TEX>$8{\mu}g/L$</TEX> of TBT concentration was significantly lower than that of control group fish. The major hematological findings were significant decreases in the red blood cell count, hematocrit value and hemogobin concentration in the fish exposed to <TEX>$8{\mu}g/L$</TEX>. Although serum glucose concentration was significantly reduced compared to the control group, total protein concentration was found to be significantly increased over the control group. Exposure to <TEX>$8{\mu}g/L$</TEX> of TBT concentration resulted in significant increase in the enzyme activities, such as glutamic oxalate transminase and glutamic pyruvate transminase in the fish. The present findings suggest that exposure to <TEX>$8{\mu}g/L$</TEX> concentration of TBT can cause significant changes in growth and hematological parameters of rock bream Oplegnathus fasciatuso.