Abstract
In Japan, the Japanese encephalitis virus (JEV), one of mosquito-borne flaviviruses, has been widely endemic on the main and on the southern islands with more than 1,000 Japanese encephalitis (JE) cases reported annually in the late 1960s. In contrast, until 1993, no TBE case had ever been reported and it was considered that there was no endemic focus of TBEV.
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