Abstract

Malformation of cortical development (MCD) is an important cause of children′s intellectual motor development disorder and refractory epilepsy.The classification of MCD is very complex, whether from the dimensions of embryonic development, genetic regulation abnormality or tissue structure characteristics.This article is mainly based on an updated version of Barkovich′s MCD classification.This framework help clinic to understand various types of MCD, search its genetic causes, and select appropriate surgical treatment for some treatable refractory epilepsy with MCD. Key words: Malformation of cortical development; Epilepsy; Developmental disorder

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