Tat veya Koku Kaybı Gelişen COVID-19 Hastalarında Makula, Retina Sinir Lifi ve Ganglion Hücre Kompleksi Kalınlıklarının Değerlendirilmesi: Kesitsel Çalışma

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Objective: To evaluate whether the presence of anosmia or ageusia associates with the thicknesses of the macula, peripapillary retinal nerve fiber layer (pRNFL), and ganglion cell complex (GCC) in patients diagnosed with coronavirus disease-2019 (COVID-19) who had fully recovered. Material and Methods: This study was conducted on 123 eyes of 123 participants. Only the right eyes of all subjects were included in the study. Group 1 consisted of 35 eyes of 35 patients with anosmia or ageusia who had recovered from COVID-19 and Group 2 consisted of 31 eyes of 31 patients without anosmia or ageusia who had recovered from COVID-19. Group 3 consisted of 57 eyes of 57 healthy subjects who were age matched with the study groups. The macula, pRNFL, and GCC thicknesses measured by optical coherence tomography were recorded and compared between groups. One-Way ANOVA test and Independent sample t-test were used to compare examinations between all groups. Results: Inferior pRNFL and average and inferior GCC values in Group 1 were significantly higher than Group 3 (p=0.001, p=0.044, p=0.017, respectively). There was no difference in macula thickness between all groups. Conclusion: In this study, we found that the GCC and pRNFL thicknesses in patients with anosmia or ageusia who had recovered from COVID-19 were significantly higher than those of healthy individuals. Anosmia or ageusia symptoms may be associated with increased pRNFL and GCC thickness in COVID-19 patients.